Monday, April 29, 2013

Lawmakers: Syria chemical weapons could menace US

House Intelligence Committee Chairman Rep. Mike Rogers, R-Mich., walks to a meeting on Capitol Hill in Washington, Friday, April 26, 2013, with Secretary of State John Kerry as he and national intelligence advisers came to the Capitol to update members of the House on Syria's alleged use of poisonous gas in its ongoing civil war. U.S. intelligence has concluded with "varying degrees of confidence," that the Syrian government has twice used chemical weapons in its fierce civil war, the White House and other top administration officials said Thursday. (AP Photo/J. Scott Applewhite)

House Intelligence Committee Chairman Rep. Mike Rogers, R-Mich., walks to a meeting on Capitol Hill in Washington, Friday, April 26, 2013, with Secretary of State John Kerry as he and national intelligence advisers came to the Capitol to update members of the House on Syria's alleged use of poisonous gas in its ongoing civil war. U.S. intelligence has concluded with "varying degrees of confidence," that the Syrian government has twice used chemical weapons in its fierce civil war, the White House and other top administration officials said Thursday. (AP Photo/J. Scott Applewhite)

(AP) ? Syria's stockpile of chemical weapons could be a greater threat after that nation's president leaves power and could end up targeting Americans at home, lawmakers warned Sunday as they considered a U.S. response that stops short of sending military forces there.

U.S. officials last week declared that the Syrian government probably had used chemical weapons twice in March, newly provocative acts in the 2-year civil war that has killed more than 70,000 people and displaced hundreds of thousands more. The U.S. assessment followed similar conclusions from Britain, France, Israel and Qatar ? key allies eager for a more aggressive response to the Syrian conflict.

President Barack Obama has said Syria's likely action ? or the transfer of President Bashar Assad's stockpiles to terrorists ? would cross a "red line" that would compel the United States to act.

Lawmakers sought to remind viewers on Sunday news programs of Obama's declaration while discouraging a U.S. foothold on the ground there.

"The president has laid down the line, and it can't be a dotted line. It can't be anything other than a red line," said House Intelligence Committee Chairman Rep. Mike Rogers, R-Mich. "And more than just Syria, Iran is paying attention to this. North Korea is paying attention to this."

Added Sen. Saxby Chambliss, R-Ga.: "For America to sit on the sidelines and do nothing is a huge mistake."

Obama has insisted that any use of chemical weapons would change his thinking about the United States' role in Syria but said he didn't have enough information to order aggressive action.

"For the Syrian government to utilize chemical weapons on its people crosses a line that will change my calculus and how the United States approaches these issues," Obama said Friday.

But Rep. Jan Schakowsky, an Illinois Democrat, said Sunday the United States needs to consider those weapons. She said that when Assad leaves power, his opponents could have access to those weapons or they could fall into the hands of U.S. enemies.

"The day after Assad is the day that these chemical weapons could be at risk ... (and) we could be in bigger, even bigger trouble," she said.

Both sides of the civil war already accuse each other of using the chemical weapons.

The deadliest such alleged attack was in the Khan al-Assal village in the Aleppo province in March. The Syrian government called for the United Nations to investigate alleged chemical weapons use by rebels in the attack that killed 31 people.

Syria, however, has not allowed a team of experts into the country because it wants the investigation limited to the single Khan al-Assal incident, while U.N. Secretary-General Ban Ki-moon has urged "immediate and unfettered access" for an expanded investigation.

One of Obama's chief antagonists on Syria, Sen. John McCain, R- Ariz., said the United States should go to Syria as part of an international force to safeguard the chemical weapons. But McCain added that he is not advocating sending ground troops to the nation.

"The worst thing we could do is put boots on the ground," McCain said.

His friend, Sen. Lindsey Graham, R-S.C., also said the United States could safeguard the weapons without a ground force. But he cautioned the weapons must be protected for fear that Americans could be targeted. Raising the specter of the lethal bomb at the finish line of the Boston Marathon, Graham said the next attack on U.S. soil could employ weapons that were once part of Assad's arsenal.

"The next bomb that goes off in America may not have nails and glass," he said.

Rogers and Schakowsky spoke to ABC's "This Week." Chambliss and Graham were interviewed on CBS's "Face the Nation." McCain appeared on NBC's "Meet the Press."

___

Follow Philip Elliott on Twitter: https://twitter.com/Philip_Elliott

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-04-28-US-Syria/id-282719b58ce349b481c3d3ac90c87902

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Hagel: US assessing reported Syrian chemical use

(AP) ? The U.S. and its allies are still trying to figure out details of Syria's suspected use of chemical weapons against its own people, Defense Secretary Chuck Hagel said Monday, as international officials pressed for broader access to suspected attack sites.

Speaking to Pentagon reporters, Hagel refused to discuss any military options including whether or not the U.S. would be willing to take unilateral action against the Syrian regime or if the administration would act only in concert with allies.

The Obama administration said last week that U.S. intelligence had concluded that Syrian government forces likely used chemical agents against rebels in two attacks, but said there were "varying degrees of confidence" about how large an attack it may have been.

Since then the administration has come under withering criticism from members of Congress demanding that the U.S. take steps to protect the Syrian people by setting up either a safe zone or a no-fly zone over at least parts of the country.

"We are continuing to assess what happened -- when, where," said Hagel. "I think we should wait to get the facts before we make any judgments on what action, if any should be taken, and what kind of action."

U.S. officials, including Secretary of State John Kerry, have said that chemical weapons ? likely the nerve agent sarin ? were used on two occasions.

Syria wants any investigation limited to an incident in the Khan al-Assal village in the Aleppo province in March that reportedly killed 31 people, but U.N. Secretary-General Ban Ki-moon wants a broader investigation, that would include a December incident in Homs.

Britain, France, Israel and Qatar also believe chemical weapons have been used in Syria's two-year-old civil war. President Barack Obama has said that use of chemical weapons by President Bashar Assad's regime, or the transfer of those stockpiles to terrorists would cross a "red line" and have "enormous consequences."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-04-29-US-US-Syria/id-e40b81551b884197bc937b48318b6727

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Bissau leader pledges election by year end

BISSAU (Reuters) - Guinea-Bissau's interim leader returned home on Sunday after weeks abroad seeking medical treatment and pledged to organize elections in his coup-prone nation before the end of the year.

President Manuel Serifo Nhamadjo refused to comment on this month's U.S. drug sting that targeted his country's top brass, accused of trafficking Latin American cocaine, but said he expected leaders to unite so donors could fund the election.

African and Western diplomats are pinning their hopes on the election drawing a line under decades of instability in the former Portuguese colony, but a U.S. sting operation that targeted the military chief sent shockwaves through the tiny nation.

"Presidential elections will take place this year," Nhamadjo told reporters after he returned from weeks of treatment in Germany for an unspecified medical problem.

"The political parties will come together to set up, as soon as possible, a unity government," he added.

The nation was thrust into its latest crisis last year when the military arrested then Prime Minister Carlos Gomes Junior and acting President Raimundo Pereira in the midst of an election that Gomes Junior was poised to win.

Armed Forces Chief General Antonio Indjai was briefly in power before officially ceding to Nhamadjo.

However, Indjai is still widely seen as the nation's most powerful man and was targeted by, but escaped, the U.S. sting operation that netted the country's former navy chief.

Nhamadjo refused to comment on the sting operation, which has led to authorities during his absence accusing Washington of illegally kidnapping one of the country's citizens.

"I was away from the country ... I was never briefed on this issue while I was away," he said.

Elections were due to be held in May, but in March West African leaders prolonged the mandate of the caretaker government until the end of the year.

(Reporting by Alberto Dabo; Writing by David Lewis; Editing by Jon Hemming)

Source: http://news.yahoo.com/bissau-leader-pledges-election-end-220526676.html

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Sunday, April 28, 2013

Uncomplicated Tips To Making The Most Ideal Real Estate ...

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Officials: No sign 'Misha' tied to Boston bombing (The Arizona Republic)

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Fargo students forgo class to help with flood prep

FARGO, N.D. (AP) ? Hundreds of high school students pitched in Friday to place 100,000 sandbags around Fargo and help protect homes against Red River flooding.

The familiar sandbag party that kicked off what city officials call "tuck it in weekend" began in 2009 when residents fought the first of three straight major floods. Students placed 700,000 sandbags in less than two days during the last flood in 2011. Officials and residents hope not nearly as many are needed this year.

The students sandbagged 134 homes throughout the city Friday and headed back to school after lunch was served by grateful residents such as Glenda Bro. About 40 students, mostly from Fargo North, laughed and sang as they tossed sandbags outside the home where Bro and her husband, a Fargo physician, have lived for 32 years.

Bro said it was a relief to have the sandbagging help, which she called "organized and calm." The singing helped.

"That's kind of contagious," Bro said. "Fear is contagious, and so is a happy spirit."

The city has reason to be optimistic.

The latest forecast calls for the Red River to reach a water level between 37 and 39 feet, down a foot from the previous crest range. Although the river begins to spill its banks at 18 feet, few structures are threatened until the water level goes above 38 feet, thanks primarily to increased flood protection efforts in recent years.

"The bottom line is we're in excellent shape to meet the crisis of 2013," said Dennis Walaker, Fargo mayor.

The river measured 21.7 feet at 2 p.m. Friday. Tim Mahoney, Fargo's deputy mayor, said the city would be buttoned up by the end of the weekend, then officials will monitor the river on an hourly basis.

"This weekend what we want to do is tuck it in, which means get all our dikes done, get all our sandbagging done, get everything done," Mahoney said. "And then we wait and watch."

Many students were happy to be outside on what was the first day where temperatures had reached into the 60s this year.

Fargo North student Ross Ashland, 17, also said he felt good about sandbagging because he was forced to evacuate his house during a record flood in 2009. He was also happy to be outside in a T-shirt for the "first time since winter started."

Another North student, Tristin Schoenwald, 16, said most of his classmate wanted to start sandbagging Thursday but weren't complaining about a lower river crest prediction.

"We're happy to help," he said. "The community has always been there for us. It's nice to return the favor."

One 13-year-old sandbagger, Brooke Peterson, is home-schooled student whose friend lives in the neighborhood.

"It's great to help. I love it," she said. "It's a great workout and I'm getting fresh air."

City worker Jim Mohr, who directed sandbag placement behind the Bro home, said the students were extremely coachable.

"They get it down pretty quickly," Mohr said. "It's great to have them."

Although workers placed down plywood in an effort to limit damage to the neighborhoods, it wasn't an issue around Bro's house because it won't be around for long. Not too long ago, the city told her the house was low on the priority list for a buyout. But last Saturday, the city agreed to take it off their hands.

"That is an answered prayer because this house wouldn't sell," Bro said. "Nobody is going to buy a house on the river in Fargo."

___

Follow Dave Kolpack on Twitter at http://www.twitter.com/davekolpackap .

Source: http://news.yahoo.com/fargo-students-forgo-class-help-flood-prep-200900829.html

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The Trials of Muhammad Ali: Tribeca Review - The Hollywood ...

The Bottom Line

An invigorating doc brings the long-forgotten controversy to life.

Venue

Tribeca Film Festival, Special Events

Director

Bill Siegel

Singling out the most dramatic period in a career that was never short on color, Bill Siegel's The Trials of Muhammad Ali focuses on a time not only before Ali's iconic status was assured, but when even the fame brought by his 1960 Olympic gold medal was in danger of being overshadowed by the inflammatory rhetoric surrounding his embrace of Islam. The film captures the thrill of Ali's personality even for viewers with little interest in the sweet science, and is meaty enough to merit arthouse bookings on its way to small screens.

Siegel starts his film in savvy fashion, contrasting a poignant scene from the height of Ali's infamy -- a British chat show on which he sits calmly while David Susskind declares, "I find nothing ... tolerable about this man ... a simplistic fool and a pawn" -- with the sight, decades later, of George W. Bush awarding him the Medal of Freedom.

Both Ali and America changed in the years between those episodes, but Trials is most interested in what could provoke reactions like Susskind's, especially given how warmly the boxer was embraced at first. In a few well-chosen clips, we are reminded how Cassius Clay won fans at the start of his career, and how charismatic he could be when interviewed. We learn a bit about his Louisville youth and the team of eleven white investors who backed his professional aspirations, but the real story begins when Clay, working in Miami, grows increasingly interested in the Nation of Islam.

Interviewing men like "Captain Sam," a close friend during this period, Siegel shows how fully the athlete embraced the teachings of Elijah Muhammad and how incensed he was when, after he was given his new name, boxing opponents refused to use it. New York Times writer Robert Lipsyte, who covered Ali for years, recalls the "truly terrible moment in the history of boxing" when Ali made a point of punishing Floyd Patterson in the ring, beating him beyond the point where the fight should've ended.

(The lighter side of Clay's transformation into Ali comes via Khalilah Camacho-Ali, who recalls meeting the man she would later marry and tearing up the autograph he had just given her, telling Cassius Clay he needed to learn his true identity.)

Siegel, who as co-director of The Weather Underground proved adept at capturing the cultural/political flavor of a moment in history, does so again here -- bringing to life not just Ali's fervent (some say unsophisticated) espousal of Nation of Islam dogma and his response to the falling-out between Elijah Muhammad and Malcolm X, but the way the nation's shifting mood made Ali's rejection of the draft a seemingly fatal PR move.

Siegel's film follows the literal trials that followed -- with Ali receiving a five-year prison sentence that would be overturned years later by the Supreme Court -- but is more interested in the effect legal and reputation issues had on Ali's livelihood: Rejected by state boxing commissions, he tried setting up bouts everywhere from Alcatraz to a stripped-out airliner that would fly above states' jurisdictions.?

Trials?has a lot to juggle during years when Ali kept afloat with speaking engagements and side gigs (including a strange quasi-musical play, seen briefly here), and the doc's focus briefly turns hazy. Glossing over the fighter's return to the ring and the decades since, the film touches on the evolution of Ali's racial ideology -- which at one point was so rigid he told an interviewer that he truly believed all white people were devils -- without getting into specifics.

But the film mostly ignores the question of how America came back around to idolizing him, letting a few images do the talking. Closing footage of Ali -- made shaky by Parkinson's but still regal -- lighting the Olympic torch in 1996, is more moving than any talking-head testimony could be.

Production Company: Kartemquin Films

Director: Bill Siegel

Producers: Rachel Pikelny, Bill Siegel

Executive producers: Leon Gast, Kat White, Sally Jo Fifer, Justine Nagan, Gordon Quinn

Music: Joshua Abrams

Editor: Aaron Wickenden

Sales: Bill Siegel, Kartemquin Films

No rating, 86 minutes

Source: http://www.hollywoodreporter.com/review/trials-muhammad-ali-tribeca-review-447388

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Saturday, April 27, 2013

Serbian lawmakers vote to support Kosovo deal

BELGRADE, Serbia (AP) ? Serbian lawmakers on Friday overwhelmingly supported an agreement normalizing relations with breakaway Kosovo, a potentially landmark deal that could end years of tensions between the Balkan antagonists and put them both on a path to European Union membership.

Parliament backed the deal in a 173-24 vote. The agreement drew support from the parties of the ruling, nationalist-led government and the center-left opposition. A pro-Russian, nationalist party was the only group that voted against it.

Parliamentary backing is a boost for the Serbian government, which reached the agreement with Kosovo this month in Brussels, but has faced pressure from nationalists and Serb hardliners in Kosovo's divided north, who rejected it.

"This is not just a simple vote about the agreement," Prime Minister Ivica Dacic told lawmakers at the end of the daylong, heated debate. "This vote shows what we stand for and which way we want to go."

Serbia has rejected Kosovo's 2008 declaration of independence ? which has been recognized by more than 90 countries including the U.S. and 22 of the EU's 27 members ? but it must improve ties with the former province to advance its bid to join the EU.

"The agreement with Pristina has sent a strong message across the whole of Europe about Serbia's European attitude," EU Enlargement Commissioner Stefan Fule said earlier Friday during a visit to Belgrade. "Serbia moved beyond past conflicts and closer to the future within Europe."

The deal will give Kosovo's ethnic Albanian leadership authority over rebel Kosovo Serbs, ending Serbia's control in northern Kosovo. The Serbs, in return, will be granted wide-ranging autonomy.

Nationalists have insisted that this amounted to treason. Slobodan Samardzic, a lawmaker from nationalist Serbian Democratic Party, said during the parliamentary debate that "the agreement means our people must give up their state." Several hundred extremists rallied outside parliament amid a heavy police presence.

Dacic rejected the accusations, insisting that "we did not betray our country, we were defending it." He reiterated that Serbia will never recognize Kosovo's statehood.

"We made the move," he said. "Did you think it was easy?"

Top Serbian leaders have said a referendum on the deal is possible, counting on popular support to silence dissent and enable easier implementation on the ground in Kosovo.

Fule said that "whatever the way they chose it should not delay the process, but in the end make sure that the implementation is sustainable." He also said "effective implementation" will be key for EU member states when they decide in June whether to open accession talks with Belgrade.

Earlier, Dacic also told lawmakers that Serbia would become "Europe's North Korea" if it rejected the deal.

Serbia's warmongering policies during the 1990s turned the country into an international pariah, facing U.N. sanctions and isolation. Years of wars and crisis also severely impoverished the country's economy.

After the Kosovo agreement, the European Commission recommended opening membership negotiations with Belgrade, an important step on the EU path that Serbia hopes will pave the way for foreign investment and unblock access to the bloc's pre-entry funds.

Serbia relinquished control of most of Kosovo in 1999 when NATO chased its troops out of the region in a three-month bombing campaign. The EU has insisted on ending the partition of Kosovo between the Albanian majority and the Serb-controlled north ? about a fifth of the country.

Source: http://news.yahoo.com/serbian-lawmakers-vote-support-kosovo-deal-201504497.html

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Chemical weapons in Syria? What Obama's high bar for proof could mean

The US reluctance to join with three key allies ? Britain, France, and now Israel ? in concluding that Syria?s Bashar al-Assad has used chemical weapons in his country?s civil war confirms President Obama?s consistent wariness about US intervention in the two-year-old conflict.

Beyond that point, however, former officials and analysts are split over why Mr. Obama is so cautious about the issue ? he even refused to answer a reporter?s question on the topic Tuesday ? and what the apparently high bar the administration has set for evidence of chemical weapons use means.

?It?s a hard call as to whether the administration is trying to avoid something, or if they just don?t have the evidence,? says Wayne White, a former State Department official with experience in Middle East intelligence.

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Obama has said repeatedly since last August that Syria?s use of chemical weapons is a US ?red line? and would be a ?game changer? for the US. But now some critics say the president?s caution suggests a moving or ?fuzzy? red line.

For some, the president is simply being prudent, especially if the evidence presented so far is ?inconclusive,? as a number of senior administration officials, including Defense Secretary Chuck Hagel, have said. Obama, they add, wants to avoid a rush to judgment that turns out to be mistaken ? and which could appear to the world like a repeat of the 2003 US decision to invade Iraq over weapons of mass destruction that didn?t exist.

White House spokesman Jay Carney said Tuesday that the US is being ?extremely deliberate? in investigating and evaluating the reports of chemical weapons use. And on Wednesday in Cairo, Secretary Hagel suggested the US would not be rushed to judgment by allies, saying, ?Suspicions are one thing. Evidence is another.? He then added, ?I think we have to be very careful here before we make any conclusions.?

But for others, the reason Obama is setting the bar high ? in a situation where incontrovertible evidence could remain very difficult to come by ? is because he has no desire to ratchet up US involvement in the Syrian conflict unless forced to.

The danger of this approach, critics say, is that it encourages an increasingly desperate President Assad to test the limits of US reluctance ? perhaps even with limited, hard-to-prove use of some chemical weapons.

And even if some isolated use of chemical weapons is proved, some analysts say, Obama is still unlikely to intervene in Syria in a manner that could tip the scales in the conflict.

?Even if CW [chemical weapons] were used, [the response] will depend a bit on how much and what we?re talking about,? says Mr. White, the former State Department official.

If chemical weapons use is proven ?there will have to be some response from the administration,? he adds, ?but unless it?s indiscriminate use, I don?t see us doing something like a no-fly zone that could really make a difference.?

Given Obama?s pattern to this point of gradually ramping up humanitarian aid and non-lethal material assistance to the rebels, the administration might bow to French and British pressure to approve providing the rebels with arms, White says. ?But something like that, that might have made a difference 18 months ago, won?t be a game-changer now.?

That?s because the rebels are now so divided, and because the groups the US would be willing to arm are not the ones ? specifically the more extremist Islamist factions ? achieving advances against Assad on the battlefield.

White, who is now an adjunct scholar at the Middle East Institute in Washington, says the administration may be ?playing for time,? with its talk of deliberate evaluation of evidence, as it tries to overcome its deep divisions over how the US should approach the complex and ever-deepening Syria crisis.

But it also may be that the ?evidence? its allies have provided the US ? supposedly photos of victims with tell-tale signs of chemical-weapons contact from the Israelis, soil samples in the case of the French and British ? isn?t very convincing.

Secretary of State John Kerry said in Brussels Tuesday that Israeli Prime Minister Benjamin Netanyahu told him in a telephone conversation that he was unable to confirm assertions from Israeli Brig. Gen. Itai Brun, head of research and analysis for Israeli military intelligence, that Syria has used chemical weapons several times since the first of the year.

British military intelligence officials originally reported in late March their finding that Assad?s forces had actually used an intense military-grade tear gas in a reported attack March 19 on the city of Halab. Reports claimed that 30 people died in the attack, but the tear gas is not a chemical weapon and it was not clear what caused the deaths.

White says Iraq?s Saddam Hussein ? who used chemical weapons to kills thousands of Kurds in 1988 ? also used a military grade tear gas known as CS on Iranian troops who were advancing on the southern Iraqi city of Basra in 1982. The gas repelled the Iranian forces but did not kill them by the thousands as a nerve gas would have, White says.

The United Nations has formed an investigative group to go into Syria and determine what chemical weapons if any were used, but so far Assad is not letting the team in. And without such a team on the ground, it may remain impossible to deliver the kind of ?conclusive evidence? the Obama administration says it has yet to see.

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Source: http://news.yahoo.com/chemical-weapons-syria-obamas-high-bar-proof-could-232636199.html

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Friday, April 26, 2013

How Parkinson's disease protein acts like a virus

Apr. 25, 2013 ? A protein known to be a key player in the development of Parkinson's disease is able to enter and harm cells in the same way that viruses do, according to a Loyola University Chicago Stritch School of Medicine study.

The protein is called alpha-synuclein. The study shows how, once inside a neuron, alpha synuclein breaks out of lysosomes, the digestive compartments of the cell. This is similar to how a cold virus enters a cell during infection. The finding eventually could lead to the development of new therapies to delay the onset of Parkinson's disease or halt or slow its progression, researchers said.

The study by virologist Edward Campbell, PhD, and colleagues, was published April 25, 2013 in the journal PLOS ONE.

Alpha-synuclein plays a role in the normal functioning of healthy neurons. But in Parkinson's disease patients, the protein turns bad, aggregating into clumps that lead to the death of neurons in the area of the brain responsible for motor control. Previous studies have shown that these protein aggregates can enter and harm cells. Campbell and colleagues showed how alpha synuclein can bust out of lysosomes, small structures that collectively serve as the cell's digestive system. The rupture of these bubble-like structures, known as vesicles, releases enzymes that are toxic to the rest of the cell.

"The release of lysosomal enzymes is sensed as a 'danger signal' by cells, since similar ruptures are often induced by invading bacteria or viruses," said Chris Wiethoff, a collaborator on the study. "Lysosomes are often described as 'suicide bags' because when they are ruptured by viruses or bacteria, they induce oxidative stress that often leads to the death of the affected cell."

In a viral or bacterial infection, the deaths of such infected cells may overall be a good thing for the infected individual. But in Parkinson's disease, this same protective mechanism may lead to the death of neurons and enhance the spread of alpha-synuclein between cells in the brain, Campbell said. "This might explain the progressive nature of Parkinson's disease. More affected cells leads to the spread of more toxic alpha-synuclein aggregates in the brain," Campbell said. "This is very similar to what happens in a spreading viral infection."

Campbell stressed that these studies need to be followed up and confirmed in other models of Parkinson's disease. "Using cultured cells, we have made some exciting observations. However, we need to understand how lysosomal rupture is affecting disease progression in animal models of Parkinson's disease and, ultimately, the brains of people affected by Parkinson's disease. Can we interfere with the ability of alpha-synuclein to rupture lysosomes in these settings? And will that have a positive effect on disease progression? These are the questions we are excited to be asking next."

Jeffrey H. Kordower, PhD, professor of neurological sciences, professor of neurosurgery and director of the Research Center for Brain Repair at Rush University Medical Center, said the study "is an important finding by a group of investigators who are beginning to make their impact in the field of Parkinson's disease. This paper adds to the growing concept that alpha-synuclein, a main culprit in the cause of Parkinson's disease, can transfer from cell to cell. This paper elegantly puts a mechanism behind such a transfer. The findings will help shape the direction of Parkinson's disease research for years to come."

Campbell and Wiethoff are assistant professors in the Department of Microbiology and Immunology at Loyola University Chicago Stritch School of Medicine. Other co-authors are David Freeman (first author), Rudy Cedillos, Samantha Choyke, Zana Lukic, Kathleen McGuire, Shauna Marvin, Andrew M. Burrage and Ajay Rana of Loyola's Stritch School of Medicine; Stacey Sudholt of Missouri School of Medicine; and Christopher O'Connor of North Central College in Naperville, Il.

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The above story is reprinted from materials provided by Loyola University Health System, via Newswise.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. David Freeman, Rudy Cedillos, Samantha Choyke, Zana Lukic, Kathleen McGuire, Shauna Marvin, Andrew M. Burrage, Stacey Sudholt, Ajay Rana, Christopher O'Connor, Christopher M. Wiethoff, Edward M. Campbell. Alpha-Synuclein Induces Lysosomal Rupture and Cathepsin Dependent Reactive Oxygen Species Following Endocytosis. PLoS ONE, 2013; 8 (4): e62143 DOI: 10.1371/journal.pone.0062143

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/PgGG8Pb9iW8/130425213758.htm

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Hot Coffee Drink vs. Cold Coffee Drink - Amateur Gourmet

April 25, 2013 | By Adam Roberts | COMMENTS

IMG_7112

There?s a funny website called ?Is It Iced Coffee Weather?? that determines, based on your location, whether it?s iced coffee weather. The current prognosis for me is: ?No. Try it hot.?

This is a question I?m often asking myself because I enjoy drinking coffee every day, so much so that I drink tea in the morning in order to save my coffee drink for later on when I can get it from a coffee shop. And when I get to the counter I have to decide if I want it hot or cold. Lately, I?ve come up with a good strategy.

Instead of focusing on the external temperature I focus on my internal temperature. Am I cold on the inside or hot on the inside at this particular moment? Do I want to warm up or do I want to cool down?

That may sound silly but this strategy is close to my ?What are you craving?? strategy when deciding what to make for dinner. Both are obvious. But both are incredibly useful.

By tuning out external factors like the temperature or health and fitness, and focusing just on what you want and need at that particular moment, chances are you?ll be happier than getting the thing you think you should get. So even if it?s a relatively warm day out and everyone around you is sipping coffee through a straw, you have to ask yourself: am I chilly on the inside? If so, a warm coffee drink is the drink you should drink.

IMG_7122

Today I?m on the fence about my coffee drink. The website says ?hot? but I?m wondering if a ?short iced latte? (my latest obsession; that?s an iced latte with less milk) is the way to go. But you can?t tell me the answer, only I can tell me the answer. So please don?t even try.

Tags: coffee, drinks, Essays, temperature

Categories: Food Bits

Source: http://www.amateurgourmet.com/2013/04/hot-coffee-drink-vs-cold-coffee-drink.html

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'Monsters University' Trailer Gets The Party Going Hard

A movie like "Monsters University" pretty much explains itself. It's about monsters, the Pixar creations from "Monsters Inc." to be specific, at college. It seems like it would be simple enough, but the actual story for "Monsters University" has mostly been kept from us until a new trailer debuted today over at Yahoo! Movies. As [...]

Source: http://moviesblog.mtv.com/2013/04/25/monsters-university-trailer-2/

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Dems, GOP talk up deficit reduction, but don't act

WASHINGTON (AP) ? Liberals' loud objections to White House proposals for slowing the growth of huge social programs make it clear that neither political party puts a high priority on reducing the deficit, despite much talk to the contrary.

For years, House Republicans have adamantly refused to raise income taxes, even though U.S. taxes are historically low, and the Bush-era tax cuts were a major cause of the current deficit.

And now, top Democrats are staunchly opposing changes to Medicare and Social Security benefits, despite studies showing the programs' financial paths are unsustainable.

Unless something gives, it's hard to see what will produce the significant compromises needed to tame the federal debt, which is nearing $17 trillion.

"There's not much of an appetite for deficit reduction," said Bob Bixby of the Concord Coalition, which pushes for "responsible fiscal policy."

There might be a few small steps this year, he said, when the government again needs to raise its borrowing limit. But a "grand bargain" involving significant spending cuts and revenue increases seems unlikely, Bixby said.

He added, "It's a little depressing to hear the reactions to the president's budget, from both sides."

There was nothing surprising about Republican denunciations of Obama's proposed tax increases, which he wants to combine with spending cuts to reduce the deficit.

The newer wrinkle was the left's sharp criticism of his proposals to slow the growth in Medicare and Social Security benefits, provided Republicans agree to new revenues. Obama has offered Republicans such a deal before. But this month's budget proposal gave it a new imprimatur.

The group MoveOn.org said Wednesday that supporters "who are outraged at President Obama's proposal to cut Social Security benefits will protest and deliver petitions" this week.

Sen. Bernie Sanders, a liberal independent from Vermont, is leading a similar petition drive, opposing "any benefit cuts to Social Security, Medicare or Medicaid." The deficit, his letter says, "was primarily caused during the Bush years by two unpaid-for wars, huge tax breaks for the rich and a prescription drug program" for Medicare, funded through borrowing. He suggests that higher taxes on the wealthy are the fairest way to tackle the deficit.

Democrats cite several reasons to raise taxes on high-income households. Obama campaigned for such tax increases in 2008 and 2012 but accomplished them only partially with the "fiscal cliff" resolution of Jan. 1.

Major tax cuts in 2001 and 2003 played big roles in turning a federal budget surplus into soaring deficits, according to research by the Congressional Budget Office and others. And by many measures, the U.S. tax burden in near historic lows.

Households earning roughly the national median income paid, on average, 11.1 percent of their income in total federal taxes in 2009, the most recent year for such data. That's the lowest level in more than 30 years, the CBO says.

Nonetheless, House Republicans have placed their highest priority on refusing to raise income tax rates, effectively ranking it above all other goals.

"The president got his tax hikes on Jan. 1," House Speaker John Boehner, R-Ohio, is fond of saying. It's a reference to the $620 billion in new revenues, over 10 years, that Republicans were unable to stop because of the "fiscal cliff" law, resolved on New Year's Day.

If it's easy to make a case for higher revenues, the same is true for slowing the growth of Social Security and Medicare benefits. For decades, studies have warned of approaching trouble in these popular but costly programs, as health care costs rise and baby boomers begin to retire.

"Both Medicare and Social Security cannot sustain projected long-run program costs under currently scheduled financing, and legislative modifications are necessary to avoid disruptive consequences for beneficiaries and taxpayers," the Social Security Administration says, summarizing findings by the two programs' trustees.

"The early detection light has been going on for a while, and there has been a failure to act," Social Security trustee Charles P. Blahous recently told a House panel. If lawmakers are to preserve the programs for future retirees, he said, they will have to accept much more "political pain" than officials endured during a 1983 overhaul that included "several extremely controversial measures."

Obama has proposed an often-discussed step, which deals with government accounting in general, not just entitlement programs. If Congress agrees to higher tax revenues, the president said, he would back a slower growth calculation for cost-of-living increases for Social Security benefits, plus higher Medicare premiums for higher-income seniors.

Interest groups have criticized both ideas. AARP calls the slower cost-of-living formula a "harmful change," and urges seniors to oppose it.

American voters can largely blame themselves when Congress is more talk than action on deficit reduction. Americans routinely say they want a smaller federal debt, but not at the cost of programs they hold dear ? including Social Security and Medicare.

A CBS News poll in March found that most Americans want to cut spending and raise taxes to reduce the deficit. But 4 in 5 oppose cuts to Social Security or Medicare. And two-thirds are unwilling to have their own taxes raised in the name of deficit reduction.

When Pew Research asked which was more important ? reducing the national debt or keeping Social Security and Medicare benefits as they are now ? the public sided with safeguarding the benefits programs, 53 percent to 36 percent.

The deficit-spending partisanship continued Wednesday. On a party-line vote, House Ways and Means Committee Republicans passed a bill to protect Social Security recipients and investors in Treasury bonds if the government hits its borrowing limit and can't pay all its bills later this year. Democrats say if the federal government starts reneging on any obligations ? even if it pays bondholders ? financial markets will lose faith and the economy will tank.

Some Democrats fear a lose-lose situation if they support Obama's proposals. First, they could be attacked from the left for tweaking the programs that many Democrats see as their party's greatest legacy. And second, Republicans might accuse them of "raiding Medicare" in next year's congressional elections. That battle cry proved effective in 2010 after Obama's health care overhaul bill was passed.

Democrats call such tactics shamelessly hypocritical. Republicans, they note, have long called for reining in entitlement spending.

Boehner rebuked a top GOP campaign figure for hinting at a renewal of the "raiding Medicare" attacks. But Reince Priebus, the national Republican Party chairman, seemed eager to revive the question of whether Democratic trims to Medicare's costs amount to an unfair cut in benefits.

Source: http://news.yahoo.com/dems-gop-talk-deficit-reduction-dont-act-070757688--finance.html

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Nothing bugs these NASA aeronautical researchers

Apr. 24, 2013 ? NASA's gutsiest scientists say they don't get bugged no matter what kind of sticky situation they find themselves smashed into.

The preceding dose of hyperbole is brought to you by a team of folks at NASA's Langley Research Center in Virginia who are studying ways to prevent the remains of insect impacts from adhering to the wing of an aircraft in flight.

While the effort is undeniably a goldmine for puns, the research is serious and positive results could help NASA's aeronautical innovators achieve their goals for improving the fuel efficiency of aircraft cruising across the country.

"We are the bug team," said Mia Siochi, of the Advanced Materials and Processing Branch at Langley. "It's important work, but we also have a lot of fun with it."

Anyone who has driven through a cloud of insects knows how quickly the bug guts build up on the vehicle, causing problems with visibility, clogging the air intake and radiator, and ruining the car's exterior finish.

The problem for an airplane is that its aerodynamic design is meant to have air move very smoothly across the body and wing surfaces, which is called laminar flow. When there is a disruption in that laminar flow, such as from the accumulation of dead bug parts, you induce the opposite of laminar flow, which is turbulence.

Finding ways to maintain laminar flow through all phases of flight is a big deal for the aviation community because it could save millions in fuel cost, while also reducing the amount of noxious emissions released into the atmosphere.

"It's major enough that people have been trying to solve this as far back as the 1960s," Siochi said.

The key to the solution of preventing insect residue build-up in flight is to find a non-stick coating or material of some kind that can be applied to an airplane's body and wings, and that will work with the unique chemistry present in a typical bug splat.

Not only is the intent to limit or prevent the initial adherence to the wing, but to increase the chances the bug residue will more easily erode or sheer off during the flight and leave the wing smooth again.

Understanding that insect biology and its interaction with airplane parts, and then coming up with a decent anti-stick coating is not as easy as you might think. For example, you can't use the same spray you might apply to your car's windshield to make rainwater bead up and roll off.

It's not just water you have to deal with.

"Yes, there's a lot of water in a bug, but there's also some biological components that actually impart the stickiness, and we have to deal with preventing those from sticking even though we know how to prevent water from sticking," Siochi said.

To help them learn more about insect adhesion to materials treated with various coatings, the bug team relies on a unique desk-sized wind tunnel -- the Basic Aerodynamic Research Tunnel, or BART -- equipped with tubing that connects from what they affectionately call "the bug gun."

It has proved to be a very effective tool for examining materials, coatings and insect splats, but the small wind tunnel doesn't exactly copy what's happening in real life.

"We're shooting bugs at about 150 mph as we try to mimic takeoff and landing speed, but the bug is moving and the target is stationary. In reality it should be the other way around," Siochi said.

Either way, the result is the same: sticky bug guts coat small wing surfaces.

Early tests show certain coatings can shrink the area that insect remains adhere to by 90 percent, and reduce the build-up, or height of the sticky bug guts, by 40 percent. But tests continue as there has been no "Eureka!" moment -- yet.

"We don't have the answer yet. We have some potential candidates, but we still have more work to do," Siochi said.

Part of the challenge, Siochi explained, is to make sure that the solution not only works, but that it is also practical.

For example, the coating should not have to be applied before every flight as that would be too time-consuming. Long term exposure of the coating on the wing or aircraft surface should not do any damage. The coating must not add so much weight that it costs more in fuel than it saves.

At least on that last point, Siochi doesn't see a problem.

"These are very, very thin coatings that we spray on, so the weight penalty is probably not there," she said.

The bug team is working toward conducting flight tests within the next two years.

All of this research by NASA does beg the question, how does a material scientist procure the insects she needs?

"By the thousands. In a tackle shop. With a credit card," Siochi explained with a smile. "After checking with our procurement officials and the legal office to make sure there were no regulations against using insects like this."

Initially, the bug team used crickets -- procured from a local tackle shop -- which were convenient to shoot uniformly in the bug gun, but also turned out to be too big for their small wind tunnel apparatus. So they switched to fruit flies.

"We get fruit flies from a fruit fly shop and we propagate them, so we have a supply of bugs that we've kept going for a couple of years now," Siochi said.

Siochi remembers one occasion when a shipment of fruit flies was delivered from California in the overnight mail, and she wasn't in the office to receive them, so they were delivered somewhere else instead.

So one of her colleagues was dispatched to hunt down this container of several hundred fruit flies and wound up searching all over Langley before finding them.

"Just another day of work for the bug team," Siochi said. "There's no doubt it's a real different kind of lab experience."

The effort is part of NASA's Environmentally Responsible Aviation project, which is managed by the agency's Aeronautics Research Mission Directorate.

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Story Source:

The above story is reprinted from materials provided by NASA.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/strange_science/~3/njQJJ78wipo/130424170125.htm

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FBI Request to Hack Computer Denied (WSJ)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, RSS Feeds and Widgets via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/301392973?client_source=feed&format=rss

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Thursday, April 25, 2013

Ohio zoo's baby monkey named for CBS TV character

POWELL, Ohio (AP) ? The Columbus Zoo's recent additions include a monkey named after a quirky scientist character on the CBS comedy "The Big Bang Theory."

The colobus monkey named Dr. Sheldon Cooper was born March 3. A spokeswoman says zoo staff pick names based on themes, and they made the TV show the latest one because they're fans.

She says keepers joke it's too soon to tell whether the monkey will live up to his namesake's brilliance.

It was the first of four recent births for the zoo's African forest exhibits.

Two red river hogs were born April 12. The month began with the birth of a black duiker (DEYE'-kur), which is a four-legged, forest-dwelling animal. It is part of the antelope family and is found in parts of Africa.

Source: http://news.yahoo.com/ohio-zoos-baby-monkey-named-cbs-tv-character-125326968.html

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Reese Witherspoon & Jim Toth -- Back to Business After ... - TMZ.com

Reese Witherspoon & Hubby
Back to Business
After Embarrassing Arrests

Exclusive

0424_reese_witherspoon_x17
Reese Witherspoon
and husband Jim Toth aren't hiding in shame following their embarrassing weekend arrests ... they're facing life head-on.

Reese was all smiles today in L.A. getting out of her car ... and Jim was back to work as usual at CAA, where he's one of Hollywood's bigwig agents.

0424_jim_toth_fame_flynet
You'll recall, Reese and Jim were both arrested in Atlanta on Friday -- Jim was popped for DUI ... and Reese was busted for disorderly conduct, after getting a little too worked up in her husband's defense.

According to police, Reese told one officer, "You're about to find out who I am ... You are going to be on national news."

Reese later released a statement, saying she was "deeply embarrassed" by what she had said.

Source: http://www.tmz.com/2013/04/24/reese-witherspoon-jim-toth-photos-pics-arrest-dui-disorderly-conduct/

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Can brain scans accurately detect lies?

If we were all like Pinocchio, it would be easy to spot when someone was telling a lie. ?Their noses would grow. ?But we?re not like Pinocchio. ? So for many years, scientists have been trying to pinpoint the telltale signs that someone is telling a tall tale.

Besides intuition or visually observing a person?s behavior, the most common method of lie detection is the polygraph. ?It?s been around since the early 1900s and measures things like your heart rate, respiration, perspiration and overall anxiety to determine if you're telling the truth.

But some scientists aren?t satisfied with that.

In this Just Explain It, we?ll look at how a new way of measuring brain activity may help researchers actually see when a person is lying.

It?s called functional magnetic resonance imaging, or fMRI. ?I know, that's a mouthful, but one company, No Lie MRI, believes the technology can expose a lie using scans of the brain?s activity. ?Here?s the theory. ?When someone tells a lie, their brain has to do more work than when they?re telling the truth ? the blood flow increases. ?fMRI scans expose that extra work. ?Areas of the brain where blood flow has increased indicate deception and are highlighted with bright colors.

The company also claims that fMRIs are accurate 90 to 99% of the time. ?That's pretty remarkable when you compare that to polygraphs, which perform with about 60% accuracy.

But studies of the brain have found that no two brains are alike - they?re like fingerprints, but more complex. ?The patterns of brain activity are actually different depending on the lie being told. ?A little white lie might look different from full on deception.?

And that leads many in the neuroscience field to think companies like No Lie MRI might themselves be stretching the truth a little bit. ?They believe more research is needed to draw indisputable conclusions on a regular basis.

The debate has also spread to the courtroom. ?Some lawyers and judges aren?t convinced the technology is foolproof either. ?In recent court cases, fMRI evidence was ruled inadmissible because the findings aren?t widely accepted by the scientific community.

In the end, the data collected might help researches begin to understand the truth about lies. ?And at some point, experts say they can see a time when brain scans will replace the polygraph. ?

But does all of this mean that people will stop telling lies?

Let us know what you think. ?Give us your feedback in the comments below or on Twitter using #YahooNews and #JustExplainIt.

Source: http://news.yahoo.com/just-explain-it--your-brain-on-lying-173120468.html

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'Big cat' was on loose in UK in 1903

A "big cat" was on the loose in the English countryside at the turn of the last century, scientists say.

They believe a Canadian lynx was prowling around the fields of the South West in 1903 before being shot after attacking two dogs in Devon.

Tests on the animal revealed it had probably spent some time in captivity before escaping or being set free.

The animal had been donated to Bristol Museum at the time of its death and kept in its stores for decades.

The scientists' findings are published in the journal Historical Biology.

Dr Ross Barnett, a molecular biologist from the University of Copenhagen and the University of Durham, said: "I've seen one of these cats in the wild.

"They are pretty impressive cats - they are a reasonable size, and they have lots of fluffy fur which makes them look even bigger. They have sharp claws, teeth and strong muscles."

Beast of Bodmin

From blurry photos of the Beast of Bodmin Moor in Cornwall, to reports of a lion on the loose in Essex in 2012, the UK has a long tradition of spotting big cats.

Most of these claims are dismissed as misidentifications, hoaxes or even hallucinations, but not in this case.

In 1903, the unusual cat was donated to the Bristol Museum and Art Gallery. The museum's records state that it had been shot after attacking and killing two dogs close to Newton Abbot in Devon.

Unsure of exactly what it was, the exotic beast was stuffed, its skeleton preserved, and then the remains were tucked away in the museum's stores.

More than a century later, the cat was unearthed by a scientist who thought the find might be significant.

An analysis of the skeleton and mounted skin revealed that the animal was a Canadian lynx, which is about the size of a dog and usually found in Canada and the northern states of the US.

The researchers found that the animal's teeth were badly decayed.

Dr Barnett said: "We think it had probably been in captivity at some point in its life.

"It had lost all of its incisors, which would have been a pretty debilitating injury for a wild cat, but not a problem for one in captivity.

"It also had massive amounts of plaque on its molars, which are indication of it not having a wild diet - something with lots of wet cat food, essentially ready-processed meat like steaks."

The researchers believe that the lynx had been in captivity for some time, but they were unable to find any records of the cat's owner.

"Was it someone's pet? Was it part of a small menagerie that was travelling through the area? There aren't really any zoos nearby where it could have escaped from," Dr Barnett said.

The team is also unsure how long the animal had been at large in Devon before it was killed.

Its decayed teeth would have limited its chances in the wild, but the lynx is an adaptable animal, and may have been able to survive by preying on small mammals.

Felicity the Puma

While many big cat sightings remain unverified, sometimes the rumours do turn out to be true, and the team believes that the Canadian lynx is the earliest recorded example of an exotic cat on the loose in the UK.

Another case relates to a live puma that was captured in Inverness-shire in 1980 and had been living in the wild for a long period of time. It was called Felicity, and placed in a zoo.

But Dr Barnett said that these cases were few and far between.

He said: "It's all very good saying you saw a lion in Essex or a tiger in Shropshire, or wherever. But it is very difficult to estimate size of a species from a distance - especially if you are unfamiliar with them.

"So I would argue for continued scepticism, unless you have a body or specimen you can analyse."

Source: http://www.bbc.co.uk/news/science-environment-22263874#sa-ns_mchannel=rss&ns_source=PublicRSS20-sa

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Mercado News Ad Likens Merkel To Hitler - Business Insider

Mercado Magazine, a small business journal, just released a series of advertisements that is begging to drum up some controversy.

One ad asks viewers to "Understand and make your own Merkel," visually indicating that Greeks view her as Hitler (presumably due to deficit debates ? Greeks did greet Merkel in Nazi uniforms when she visited Athens last year), Spaniards see her as Mother Theresa (again, presumably due to the Spanish bailout.)

Posing any politician, particularly a German one, hailing is undoubtedly meant to offend.

The same stereotypes are given to the Pope. Catholics see him as he is, Muslims don't see him at all, homosexuals see him as a club wielding cave man, and the rest of the world see him as a blank slate.

Berlusconi gets off slightly easier ? he is only compared to a Chippendale's dancer.

JWT Buenos Aires has created marketing campaigns for Mercado in the past and made this ad series as well.

Source: http://www.businessinsider.com/mercado-news-ad-likens-merkel-to-hitler-2013-4

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Wednesday, April 24, 2013

Minka Kelly Goes Blonde: Caption This Photo

Minka Kelly has gone blonde! Yep the actress has traded in her dark locks for a lighter color and I have to say she looks pretty darn good. This new change has made her the object of Right Celebrity’s Caption This photo contest for the week, woot woot! A major make-over happened for the former Friday Night Lights actress and I am going to give you my two cents on it in one hot moment. First though I want to tell you all about our Caption This photo contest. It is super easy, as I am sure you are already aware. All you have to do is take a little looksy at the above pic of Minka and caption it by leaving your witty remarks in the below comments section. Then next Tuesday when a hot new topic and picture are posted be sure to check back her to see if your name is in black and white as the big winner, woohoo! See I told you loads of fun and lets be real who doesn’t want to comment on her new look. On Monday Minka debuted a new look. It was a big change for the actress, she went [...]

Source: http://feedproxy.google.com/~r/RightCelebrity/~3/oSI7P_M5aDc/

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Costs to treat heart failure expected to more than double by 2030

Apr. 24, 2013 ? By 2030, you -- and every U.S. taxpayer -- could be paying $244 a year to care for heart failure patients, according to an American Heart Association policy statement.

The statement, published online in the American Heart Association journal Circulation: Heart Failure, predicts:

  • The number of people with heart failure could climb 46 percent from 5 million in 2012 to 8 million in 2030.
  • Direct and indirect costs to treat heart failure could more than double from $31 billion in 2012 to $70 billion in 2030.

"If we don't improve or reduce the incidence of heart failure by preventing and treating the underlying conditions, there will be a large monetary and health burden on the country," said Paul A. Heidenreich, M.D., M.S., professor of medicine at Stanford University School of Medicine and director of the Chronic Heart Failure Quality Enhancement Research Initiative at the VA Health Care System in Palo Alto, Calif.

"The costs will be paid for by every adult in this country, not just every adult with heart failure."

The rising incidence is fueled by the aging population and an increase in the number of people with conditions like ischemic heart disease, hypertension and diabetes -- contributors to the development of heart failure. Being older, a smoker, a minority or poor are also risk factors.

"Awareness of risk factors and adequately treating them is the greatest need," Heidenreich said.

Heart failure is a life-threatening condition that occurs when the heart has been weakened from heart disease, high blood pressure, diabetes and other underlying conditions, and can no longer pump enough oxygen- and nutrient-rich blood throughout the body.

Heart failure is the leading cause of hospitalization for Americans over age 65. Patients are often fatigued and have breathing problems, as the heart enlarges and pumps faster to try to meet the body's needs.

"Heart failure is a disease of the elderly," Heidenreich said. "Because our population is aging, it will become more common and the cost to treat heart failure will become a significant burden to the United States over the next 20 years unless something is done to reduce the age-specific incidence."

The statement includes recommendations on lessening the impact of heart failure and managing the rising number of Americans with the condition. These include:

  • More effective dissemination and use of guideline-recommended therapy to prevent heart failure and improve survival.
  • Improving the coordination of care from hospital to home to achieve better outcomes and reduce rehospitalizations.
  • Specialized training for physicians, nurses, pharmacists and other healthcare professionals to meet the future demands of advanced heart failure care.
  • Reducing disparities for heart failure prevention and care among racial, ethnic, and socioeconomic subgroups to help close the gap in health outcomes.
  • Increasing access to palliative and hospice care, for patients with advanced-stage heart failure.

"We have the solutions we need to change the course of heart failure in this country, but we must take steps now to reverse the trend," said American Heart Association CEO Nancy Brown. "If we treat patients using existing guidelines, improve care transitions, adequately train our healthcare workforce and reduce disparities in the health outcomes of specific populations, we can lessen the burdens of heart failure."

"For those Americans in the last stages of heart failure, we must also increase access to palliative and hospice care to reduce the suffering of their final years."

The statement doesn't examine the impact of provisions of the Affordable Care Act. If laws allow more people to have access to health care, it could lower the rates of heart failure and ultimately costs as people will have access to preventive care, Heidenreich said.

Also, being an ethnic minority and of a lower socio-economic status were both cited as risk factors for heart failure, so more access to health care may help reduce overall risk.

Co-writers of the statement are: Nancy M. Albert, Ph.D., R.N.; Larry A. Allen, M.D., M.H.S.; David A. Bluemke, M.D., Ph.D.; Javed Butler, M.D., M.P.H.; Gregg C. Fonarow, M.D.: John S. Ikonomidis, M.D., Ph.D.; Olga Khavjou, M.A.; Marvin A. Konstam, M.D.; Thomas M. Maddox, M.D., M.Sc.; Graham Nichol, M.D., M.P.H.; Michael Pham, M.D., M.P.H.; Ileana L. Pi?a, M.D., M.P.H.; and Justin G. Trogdon, Ph.D.

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Story Source:

The above story is reprinted from materials provided by American Heart Association.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Paul A. Heidenreich et al. Forecasting the Impact of Heart Failure in the United States A Policy Statement From the American Heart Association. Circulation: Heart Failure, 2013 DOI: 10.1161/HHF.0b013e318291329a

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/heart_disease/~3/iAynevOGN1o/130424112213.htm

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